Albuterol Sulfate HFA Inhaler: Fast-Acting Relief for Asthma and Bronchospasm
| Product dosage: 10mg | |||
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| Product dosage: 2.5mg | |||
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| Product dosage: 20mg | |||
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| Product dosage: 5mg | |||
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Synonyms | |||
Similar products
Albuterol Sulfate HFA Inhaler is a trusted, prescription-only bronchodilator designed for rapid relief of acute bronchospasm. It works by relaxing the muscles in the airways, allowing improved airflow within minutes of administration. This guide provides a comprehensive overview of its medical uses, proper dosing, safety considerations, and clinical benefits to support informed patient and provider decision-making.
Features
- Contains albuterol sulfate, a short-acting beta2-adrenergic agonist (SABA)
- Hydrofluoroalkane (HFA) propellant, chlorofluorocarbon-free
- Delivers 90 mcg per actuation
- Compact, portable metered-dose inhaler (MDI) design
- Integrated dose counter to track remaining medication
- Compatible with valved holding chambers (spacers) for improved delivery
Benefits
- Provides rapid relief from acute asthma symptoms and exercise-induced bronchospasm
- Helps restore normal breathing patterns within minutes of use
- Reduces frequency and severity of bronchospastic episodes
- Supports active lifestyles by preventing exercise-induced symptoms
- Minimizes emergency department visits through effective symptom management
- Enhances overall quality of life by improving respiratory function
Common use
Albuterol Sulfate HFA Inhaler is primarily indicated for the treatment or prevention of bronchospasm in patients with reversible obstructive airway disease, including asthma. It is also FDA-approved for the prevention of exercise-induced bronchospasm. Healthcare providers may prescribe it off-label for other respiratory conditions involving bronchoconstriction, though such use should be carefully supervised. The inhaler is intended for symptomatic relief rather than as a maintenance medication for long-term asthma control.
Dosage and direction
For treatment of acute bronchospasm in adults and children aged 4 years and older: 1–2 inhalations every 4–6 hours as needed. For prevention of exercise-induced bronchospasm: 2 inhalations 15–30 minutes before exercise. Maximum daily dosage should not exceed 8 inhalations in 24 hours for most patients, though some severe cases may warrant up to 12 inhalations under medical supervision. Always shake the inhaler well before each use. Prime the inhaler before first use or if not used for more than 2 weeks by releasing 4 test sprays into the air away from the face. Exhale fully before placing mouthpiece in mouth, inhale slowly and deeply while pressing down on the canister, hold breath for 10 seconds if possible, then exhale slowly. Wait at least 30–60 seconds between inhalations. Rinse mouth with water after use to minimize systemic absorption and potential side effects.
Precautions
Use with caution in patients with cardiovascular disorders (especially coronary insufficiency, cardiac arrhythmias, and hypertension), hyperthyroidism, diabetes mellitus, or seizure disorders. Monitor for paradoxical bronchospasm—if it occurs, discontinue immediately and institute alternative therapy. Excessive use may lead to loss of effectiveness and potentially fatal bronchospasm; increasing need for medication may indicate deteriorating asthma control requiring reassessment of therapy. Not recommended as the sole agent for patients with status asthmaticus or other acute episodes requiring intensive measures. Use during labor should be carefully considered as albuterol may interfere with uterine contractility. Elderly patients may be more sensitive to beta-agonist effects.
Contraindications
Hypersensitivity to albuterol sulfate or any component of the formulation. Contraindicated in patients with a history of hypersensitivity to other beta-agonists. Not recommended for patients with tachyarrhythmias or those experiencing episodes of status asthmaticus that are unresponsive to initial bronchodilator therapy.
Possible side effect
Common side effects (≥1%) include: nervousness, headache, throat irritation, cough, tachycardia, palpitations, muscle cramps, nausea, dizziness, and tremor. Less frequent side effects may include: paradoxical bronchospasm, hypertension, hypokalemia, hyperglycemia, insomnia, and vomiting. Allergic reactions including rash, hives, and angioedema are rare but possible. Immediately report any chest pain, irregular heartbeat, or worsening breathing difficulties.
Drug interaction
May interact significantly with: beta-blockers (may antagonize bronchodilating effects and produce severe bronchospasm), diuretics (may potentiate hypokalemia), digoxin (may increase risk of arrhythmias), monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (may potentiate cardiovascular effects), other sympathomimetic agents (may increase adverse cardiovascular effects). Concurrent use with xanthine derivatives may increase the risk of adverse cardiovascular effects. Use cautiously with QT-prolonging agents.
Missed dose
If a scheduled dose is missed, administer it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for a missed one. Since albuterol is typically used as needed for symptom relief rather than on a fixed schedule, this primarily applies to preventive use before exercise. Maintain at least 4–6 hours between doses unless directed otherwise by a healthcare provider.
Overdose
Overdose may manifest as exaggeration of known side effects including angina, hypertension, hypokalemia, seizures, tachycardia with rates up to 200 beats per minute, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, malaise, and insomnia. Hypokalemia may occur due to intracellular shunting. Cardiac arrest and death may occur with extreme overdose. Treatment is supportive and symptomatic. Cardioselective beta-blockers may be considered but used with extreme caution in patients with bronchospastic disease. Monitor potassium levels and provide electrolyte supplementation as needed.
Storage
Store at room temperature between 15–30°C (59–86°F). Avoid freezing and excessive heat above 49°C (120°F). Do not puncture or incinerate the container, even when empty. Keep away from open flame or heat source—contents are under pressure. Keep the cap on the mouthpiece when not in use. Clean the mouthpiece regularly (at least weekly) by rinsing with warm water and allowing to air-dry completely before reassembly. Discard the inhaler when the counter reads “000” or after 3 months from removal from the foil pouch, whichever comes first.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting, changing, or stopping any medication. Individual patient needs may vary based on specific health conditions, other medications, and clinical circumstances. Proper diagnosis and treatment should be determined by a licensed medical provider familiar with the patient’s complete medical history.
Reviews
Clinical studies demonstrate that albuterol sulfate HFA inhaler provides effective relief of bronchospasm in 90% of patients within 15 minutes of administration. Pulmonary specialists consistently rate it as a first-line rescue medication for asthma management. Patients report high satisfaction with its rapid action and portability, though some note the taste and potential for jitteriness. The transition from CFC to HFA propellant has been largely successful with maintained efficacy and improved environmental profile. Overall, it remains a cornerstone medication in respiratory emergency kits and maintenance therapy plans worldwide.