Prednisolone: Potent Anti-Inflammatory Corticosteroid Treatment
| Product dosage: 10mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 10 | $4.53 | $45.30 (0%) | 🛒 Add to cart |
| 20 | $2.52 | $90.60 $50.33 (44%) | 🛒 Add to cart |
| 30 | $1.85 | $135.90 $55.37 (59%) | 🛒 Add to cart |
| 60 | $1.01 | $271.80 $60.40 (78%) | 🛒 Add to cart |
| 90 | $0.78 | $407.70 $70.47 (83%) | 🛒 Add to cart |
| 120 | $0.71 | $543.60 $85.57 (84%) | 🛒 Add to cart |
| 180 | $0.62 | $815.40 $110.73 (86%) | 🛒 Add to cart |
| 270 | $0.56 | $1223.10 $151.00 (88%) | 🛒 Add to cart |
| 360 | $0.48
Best per pill | $1630.81 $171.13 (90%) | 🛒 Add to cart |
| Product dosage: 20mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 10 | $5.03 | $50.33 (0%) | 🛒 Add to cart |
| 20 | $2.77 | $100.67 $55.37 (45%) | 🛒 Add to cart |
| 30 | $2.01 | $151.00 $60.40 (60%) | 🛒 Add to cart |
| 60 | $1.09 | $302.00 $65.43 (78%) | 🛒 Add to cart |
| 90 | $1.01 | $453.00 $90.60 (80%) | 🛒 Add to cart |
| 120 | $0.84 | $604.00 $100.67 (83%) | 🛒 Add to cart |
| 180 | $0.73 | $906.00 $130.87 (86%) | 🛒 Add to cart |
| 270 | $0.60 | $1359.00 $161.07 (88%) | 🛒 Add to cart |
| 360 | $0.49
Best per pill | $1812.01 $176.17 (90%) | 🛒 Add to cart |
| Product dosage: 40mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 10 | $6.04 | $60.40 (0%) | 🛒 Add to cart |
| 20 | $3.27 | $120.80 $65.43 (46%) | 🛒 Add to cart |
| 30 | $2.35 | $181.20 $70.47 (61%) | 🛒 Add to cart |
| 60 | $1.34 | $362.40 $80.53 (78%) | 🛒 Add to cart |
| 90 | $1.12 | $543.60 $100.67 (81%) | 🛒 Add to cart |
| 120 | $1.01 | $724.80 $120.80 (83%) | 🛒 Add to cart |
| 180 | $0.84 | $1087.20 $151.00 (86%) | 🛒 Add to cart |
| 270 | $0.65 | $1630.81 $176.17 (89%) | 🛒 Add to cart |
| 360 | $0.59
Best per pill | $2174.41 $211.40 (90%) | 🛒 Add to cart |
Similar products
Prednisolone is a synthetic glucocorticoid medication widely prescribed for its potent anti-inflammatory and immunosuppressive properties. As a cornerstone in managing numerous acute and chronic conditions, it mimics the action of cortisol, a natural hormone produced by the adrenal glands. Its therapeutic efficacy spans allergic reactions, autoimmune disorders, and inflammatory diseases, making it an indispensable tool in modern pharmacotherapy. Proper usage under medical supervision ensures optimal outcomes while minimizing risks.
Features
- Synthetic glucocorticoid with high anti-inflammatory potency
- Available in multiple formulations: oral tablets, liquid solutions, and injectables
- Rapid onset of action with systemic bioavailability
- Modulates immune response through gene expression regulation
- Standardized dosing allows for tailored therapeutic regimens
Benefits
- Rapid reduction of inflammation and associated pain
- Effective suppression of inappropriate immune responses in autoimmune conditions
- Prevents and controls allergic reactions
- Helps manage symptoms of severe asthma and chronic obstructive pulmonary disease
- Can induce remission in certain hematologic and oncologic disorders
- Provides symptomatic relief in rheumatic diseases and dermatologic conditions
Common use
Prednisolone is commonly prescribed for a broad spectrum of medical conditions including rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease. It is utilized in severe allergic reactions, asthma exacerbations, and chronic obstructive pulmonary disease management. Dermatologists employ it for conditions like severe psoriasis and contact dermatitis, while hematologists use it in treating certain leukemias and lymphomas. It also serves as adjuvant therapy in organ transplantation to prevent rejection.
Dosage and direction
Dosage varies significantly based on condition severity, patient response, and treatment duration. Initial doses for adults typically range from 5-60 mg daily, often administered as a single morning dose to mimic natural cortisol rhythm. Pediatric dosing is weight-based, generally 0.14-2 mg/kg/day divided into multiple doses. Tapering is crucial when discontinuing therapy to prevent adrenal insufficiency. Always follow prescribing physician’s instructions precisely regarding timing, duration, and tapering schedule.
Precautions
Patients should be monitored for hyperglycemia, hypertension, and electrolyte imbalances during therapy. Regular ophthalmologic examinations are recommended for those on prolonged treatment due to increased risk of cataracts and glaucoma. Bone density monitoring is advised for long-term users due to osteoporosis risk. Vaccination with live vaccines should be avoided during treatment. Caution is required in patients with history of peptic ulcers, psychiatric disorders, or seizure disorders.
Contraindications
Absolute contraindications include systemic fungal infections and known hypersensitivity to prednisolone or any component of the formulation. Relative contraindications include active peptic ulcer disease, uncontrolled hypertension, congestive heart failure, and recent intestinal anastomoses. Use during pregnancy requires careful risk-benefit assessment due to potential fetal harm. Breastfeeding while taking prednisolone requires medical supervision.
Possible side effect
Common side effects include insomnia, increased appetite, weight gain, and fluid retention. Gastrointestinal effects may include nausea, heartburn, and peptic ulcers. Endocrine effects can manifest as hyperglycemia, Cushingoid appearance, and adrenal suppression. Long-term use may lead to osteoporosis, increased infection susceptibility, and skin thinning. Psychiatric effects range from mood swings to severe depression or psychosis in susceptible individuals.
Drug interaction
Prednisolone interacts with numerous medications including anticoagulants (increased bleeding risk), antidiabetic drugs (reduced effectiveness), and diuretics (potassium depletion). Concurrent use with NSAIDs increases gastrointestinal ulcer risk. CYP3A4 inducers like phenytoin may reduce prednisolone efficacy, while inhibitors like ketoconazole may increase toxicity. Live vaccines may have reduced efficacy during therapy.
Missed dose
If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for the missed one. For once-daily dosing regimens, if remembered within 12 hours of scheduled time, take immediately; otherwise skip and resume normal schedule. For multiple daily doses, take missed dose if within 4 hours of scheduled time. Always consult prescribing physician for specific instructions regarding missed doses.
Overdose
Acute overdose may manifest as hypertension, hyperglycemia, fluid retention, and psychiatric symptoms. Chronic excessive dosing leads to Cushing’s syndrome characteristics. Treatment is supportive and symptomatic; there is no specific antidote. Hemodialysis is not effective due to high protein binding. Gastric lavage may be considered if ingestion was recent. Medical attention should be sought immediately for suspected overdose.
Storage
Store at room temperature (15-30°C) in original container, protected from light and moisture. Keep tightly closed and away from heat sources. Do not freeze liquid formulations. Keep out of reach of children and pets. Do not use beyond expiration date. Properly dispose of unused medication according to local regulations, avoiding flushing or drainage systems.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for diagnosis and treatment recommendations. Individual response to medication may vary, and proper medical supervision is essential throughout treatment. Do not initiate, modify, or discontinue therapy without physician guidance.
Reviews
Clinical studies demonstrate prednisolone’s efficacy in numerous conditions, with 70-90% of patients showing significant improvement in inflammatory markers and symptomatic relief. Rheumatoid arthritis trials show 60-80% of patients achieving disease activity reduction. Asthma studies indicate improved pulmonary function in 85% of severe cases. Long-term safety data confirms benefit-risk profile favors appropriate use under medical supervision. Patient-reported outcomes indicate improved quality of life despite potential side effects when properly managed.